{"id":1030,"date":"2015-06-05T13:31:47","date_gmt":"2015-06-05T13:31:47","guid":{"rendered":"http:\/\/lbi-cy.com\/?page_id=1030"},"modified":"2023-04-27T12:44:09","modified_gmt":"2023-04-27T12:44:09","slug":"msca-fellowship-oxford","status":"publish","type":"page","link":"https:\/\/lbi-cy.com\/?page_id=1030","title":{"rendered":"MSCA IE Fellowship Oxford"},"content":{"rendered":"

Project Synopsis<\/strong><\/p>\n

Cardiosphere-derived stem cell (CDC) therapy for myocardial infarction (MI) has been shown to elicit moderate beneficial effects. Research currently focuses on improving CDC administration, retention and efficacy. This proposal aims to develop Magnetic Resonance Imaging (MRI) and engineering tools<\/strong> to facilitate this research. Specifically, microinjection of 19<\/sup>F labeled CDCs will allow for MRI tracking and quantification in-vivo. Non-invasive global and regional cardiac function measurements will assess efficacy of stem cell (SC) therapy. \u00a0The anticipated impact will be multifaceted, including the study of cardiac function in disease, and the potential applicability of generated results with cutting edge SC regenerative technologies in heart failure and prominent cardiomyopathies. Research efforts will be stimulated in manufacturing processes for scaffolds, cardiac functional assessment post-injection of SCs, and validation of their homing, engraftment and viability using cellular tracking methods. Through a personalized career development plan, the Fellowship will allow training of the researcher in advanced cellular characterization, labeling, and bio-imaging techniques, synergistically with trans-European mobility, reinforcing his scientific, managerial and leadership qualities. Overall, the short-term objective is the advancement of the researcher\u2019s career in science and the broadening of his scientific horizons.<\/p>\n

Project Implementation<\/strong><\/p>\n

\"gant-table\"<\/p>\n

Table:<\/strong> Gantt Chart reflecting activities for proposed project work.<\/p>","protected":false},"excerpt":{"rendered":"

Project Synopsis
\nCardiosphere-derived stem cell (CDC) therapy for myocardial infarction (MI) has been shown to elicit […]<\/p>\n","protected":false},"author":1,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"footnotes":""},"class_list":["post-1030","page","type-page","status-publish","hentry"],"yoast_head":"\nMSCA IE Fellowship OxfordMSCA IE Fellowship Oxford | Dr. C. Constantinides<\/title>\n<meta name=\"description\" content=\"Project Synopsis Cardiosphere-derived stem cell (CDC) therapy for myocardial infarction (MI) has been shown to elicit moderate beneficial effects. Research currently focuses on improving CDC administration, retention and efficacy. This proposal aims to develop Magnetic Resonance Imaging (MRI) and engineering tools to facilitate this research. Specifically, microinjection of 19F labeled CDCs will allow for MRI tracking and quantification in-vivo. Non-invasive global and regional cardiac function measurements will assess efficacy of stem cell (SC) therapy. \u00a0The anticipated impact will be multifaceted, including the study of cardiac function in disease, and the potential applicability of generated results with cutting edge SC regenerative technologies in heart failure and prominent cardiomyopathies. Research efforts will be stimulated in manufacturing processes for scaffolds, cardiac functional assessment post-injection of SCs, and validation of their homing, engraftment and viability using cellular tracking methods. Through a personalized career development plan, the Fellowship will allow training of the researcher in advanced cellular characterization, labeling, and bio-imaging techniques, synergistically with trans-European mobility, reinforcing his scientific, managerial and leadership qualities. Overall, the short-term objective is the advancement of the researcher\u2019s career in science and the broadening of his scientific horizons. Project Implementation Table: Gantt Chart reflecting activities for proposed project work.\" \/>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/lbi-cy.com\/?page_id=1030\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"MSCA IE Fellowship OxfordMSCA IE Fellowship Oxford | Dr. C. Constantinides\" \/>\n<meta property=\"og:description\" content=\"Project Synopsis Cardiosphere-derived stem cell (CDC) therapy for myocardial infarction (MI) has been shown to elicit moderate beneficial effects. Research currently focuses on improving CDC administration, retention and efficacy. This proposal aims to develop Magnetic Resonance Imaging (MRI) and engineering tools to facilitate this research. Specifically, microinjection of 19F labeled CDCs will allow for MRI tracking and quantification in-vivo. Non-invasive global and regional cardiac function measurements will assess efficacy of stem cell (SC) therapy. \u00a0The anticipated impact will be multifaceted, including the study of cardiac function in disease, and the potential applicability of generated results with cutting edge SC regenerative technologies in heart failure and prominent cardiomyopathies. Research efforts will be stimulated in manufacturing processes for scaffolds, cardiac functional assessment post-injection of SCs, and validation of their homing, engraftment and viability using cellular tracking methods. Through a personalized career development plan, the Fellowship will allow training of the researcher in advanced cellular characterization, labeling, and bio-imaging techniques, synergistically with trans-European mobility, reinforcing his scientific, managerial and leadership qualities. Overall, the short-term objective is the advancement of the researcher\u2019s career in science and the broadening of his scientific horizons. Project Implementation Table: Gantt Chart reflecting activities for proposed project work.\" \/>\n<meta property=\"og:url\" content=\"https:\/\/lbi-cy.com\/?page_id=1030\" \/>\n<meta property=\"og:site_name\" content=\"Dr. C. Constantinides\" \/>\n<meta property=\"article:modified_time\" content=\"2023-04-27T12:44:09+00:00\" \/>\n<meta property=\"og:image\" content=\"https:\/\/lbi-cy.com\/wp-content\/uploads\/2015\/06\/gant-table.jpg\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\\\/\\\/schema.org\",\"@graph\":[{\"@type\":\"WebPage\",\"@id\":\"https:\\\/\\\/lbi-cy.com\\\/?page_id=1030\",\"url\":\"https:\\\/\\\/lbi-cy.com\\\/?page_id=1030\",\"name\":\"MSCA IE Fellowship OxfordMSCA IE Fellowship Oxford | Dr. C. 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Non-invasive global and regional cardiac function measurements will assess efficacy of stem cell (SC) therapy. \u00a0The anticipated impact will be multifaceted, including the study of cardiac function in disease, and the potential applicability of generated results with cutting edge SC regenerative technologies in heart failure and prominent cardiomyopathies. Research efforts will be stimulated in manufacturing processes for scaffolds, cardiac functional assessment post-injection of SCs, and validation of their homing, engraftment and viability using cellular tracking methods. Through a personalized career development plan, the Fellowship will allow training of the researcher in advanced cellular characterization, labeling, and bio-imaging techniques, synergistically with trans-European mobility, reinforcing his scientific, managerial and leadership qualities. 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Non-invasive global and regional cardiac function measurements will assess efficacy of stem cell (SC) therapy. \u00a0The anticipated impact will be multifaceted, including the study of cardiac function in disease, and the potential applicability of generated results with cutting edge SC regenerative technologies in heart failure and prominent cardiomyopathies. Research efforts will be stimulated in manufacturing processes for scaffolds, cardiac functional assessment post-injection of SCs, and validation of their homing, engraftment and viability using cellular tracking methods. Through a personalized career development plan, the Fellowship will allow training of the researcher in advanced cellular characterization, labeling, and bio-imaging techniques, synergistically with trans-European mobility, reinforcing his scientific, managerial and leadership qualities. 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